Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 1558 0.287 0.962 3.7E-02 0.700 None 0.983 173 2 1991 2020
Entrez Id: 4087
Gene Symbol: SMAD2
SMAD2
Q15796 SMAD family member 2 Transcription factor 289 0.456 0.808 1.00 0.100 None 1.000 13 0 2013 2020
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
P84022 SMAD family member 3 Transcription factor 470 0.415 0.923 0.80 0.100 None 1.000 13 0 2005 2020
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.100 None 1.000 13 1 2009 2020
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.600 None 1.000 12 0 2009 2020
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.100 None 1.000 12 0 2011 2020
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.100 None 1.000 11 0 2013 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.100 None 1.000 11 0 2013 2020
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.100 None 1.000 11 0 2013 2020
Entrez Id: 10631
Gene Symbol: POSTN
POSTN
Q15063 periostin Signaling 378 0.428 0.885 1.1E-09 0.100 None 1.000 10 0 2012 2020
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
P09429 high mobility group box 1 Nucleic acid binding 724 0.368 0.923 0.82 0.390 None 0.900 10 0 2008 2020
Entrez Id: 207
Gene Symbol: AKT1
AKT1
P31749 AKT serine/threonine kinase 1 Kinase 1250 0.311 0.962 0.98 0.080 None 0.875 8 0 2015 2020
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.080 None 1.000 8 0 2016 2020
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
O00206 toll like receptor 4 1174 0.321 0.962 4.6E-09 0.080 None 1.000 8 0 2015 2020
Entrez Id: 7070
Gene Symbol: THY1
THY1
P04216 Thy-1 cell surface antigen 197 0.496 0.808 5.0E-02 0.060 None 1.000 6 0 2008 2020
Entrez Id: 2735
Gene Symbol: GLI1
GLI1
P08151 GLI family zinc finger 1 369 0.431 0.846 7.7E-14 0.060 None 1.000 6 0 2012 2020
Entrez Id: 1056
Gene Symbol: CEL
CEL
P19835 carboxyl ester lipase 172 0.514 0.808 1.5E-06 0.050 None 0.800 5 0 2011 2020
Entrez Id: 10998
Gene Symbol: SLC27A5
SLC27A5
Q9Y2P5 solute carrier family 27 member 5 Transporter 111 0.563 0.769 8.4E-15 0.050 None 0.800 5 0 2011 2020
Entrez Id: 83666
Gene Symbol: PARP9
PARP9
Q8IXQ6 poly(ADP-ribose) polymerase family member 9 116 0.554 0.808 5.0E-09 0.050 None 0.800 5 0 2011 2020
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
O60674 Janus kinase 2 Kinase 644 0.385 0.885 0.65 0.050 None 1.000 5 0 2017 2020
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 1034 0.322 0.923 4.5E-04 0.030 None 1.000 3 0 2019 2020
Entrez Id: 6868
Gene Symbol: ADAM17
ADAM17
P78536 ADAM metallopeptidase domain 17 316 0.453 0.808 1.00 0.030 None 1.000 3 0 2018 2020
Entrez Id: 10859
Gene Symbol: LILRB1
LILRB1
Q8NHL6 leukocyte immunoglobulin like receptor B1 Receptor 168 0.510 0.769 5.7E-14 0.020 None 1.000 2 0 2018 2020
Entrez Id: 3491
Gene Symbol: CCN1
CCN1
O00622 cellular communication network factor 1 Signaling 246 0.473 0.731 0.71 0.020 None 1.000 2 0 2016 2020
Entrez Id: 406984
Gene Symbol: MIR200B
MIR200B
microRNA 200b 180 0.500 0.769 0.020 None 1.000 2 0 2018 2020